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Doses might be enhanced slowly as needed and tolerated, but need to be limited to the smallest helpful quantity.Management of picked, refractory sufferers with epilepsy on stable regimens of antiepileptic medications who need intermittent use of the drug to regulate bouts of elevated seizure activityAs a consequence of these challenges, reserve con

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Serotonin syndrome: Scenarios of serotonin syndrome, a likely lifetime-threatening condition, have been noted all through concomitant usage of opioids with serotonergic medicines.Tramadol incorporates a danger for abuse and addiction, which may result in overdose and death. Tramadol could also cause severe, potentially lethal, respiration complicat

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